BDBM50115082 3-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-piperidine-1-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL50535

SMILES COc1cccc(NC(=O)N2CCCC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1

InChI Key InChIKey=ONWGMJQANDWQQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50115082   

TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50115082(3-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-piper...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition if C-C chemokine receptor type 3 (CCR3) using 150p M [125I]-labeled human eotaxinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50115082(3-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-piper...)
Affinity DataIC50: 820nMAssay Description:In vitro C-C chemokine receptor type 3 receptor activity of compound to inhibit eotaxin induced [Ca2+] mobilization in human eosinophil chemotaxis as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed