BDBM50115563 4-(4-Chloro-phenyl)-1-(2-ethoxycarbonyl-ethyl)-piperidine-3-carboxylic acid methyl ester::CHEMBL105921

SMILES CCOC(=O)CCN1CC[C@@H](C(C1)C(=O)OC)c1ccc(Cl)cc1

InChI Key InChIKey=DBQZRVQSIMTCRY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115563   

TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115563(4-(4-Chloro-phenyl)-1-(2-ethoxycarbonyl-ethyl)-pip...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115563(4-(4-Chloro-phenyl)-1-(2-ethoxycarbonyl-ethyl)-pip...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115563(4-(4-Chloro-phenyl)-1-(2-ethoxycarbonyl-ethyl)-pip...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed