BDBM50115718 1-Phenyl-4-(4-phenylethynyl-1H-pyrrol-2-ylmethyl)-piperazine::CHEMBL58662

SMILES C(N1CCN(CC1)c1ccccc1)c1cc(c[nH]1)C#Cc1ccccc1

InChI Key InChIKey=VZNBDFOHHGDJKC-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50115718   

TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115718(1-Phenyl-4-(4-phenylethynyl-1H-pyrrol-2-ylmethyl)-...)
Affinity DataKi:  83nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D4 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115718(1-Phenyl-4-(4-phenylethynyl-1H-pyrrol-2-ylmethyl)-...)
Affinity DataKi:  550nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D2 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115718(1-Phenyl-4-(4-phenylethynyl-1H-pyrrol-2-ylmethyl)-...)
Affinity DataKi:  670nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D3 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115718(1-Phenyl-4-(4-phenylethynyl-1H-pyrrol-2-ylmethyl)-...)
Affinity DataKi:  760nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D2 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115718(1-Phenyl-4-(4-phenylethynyl-1H-pyrrol-2-ylmethyl)-...)
Affinity DataKi:  2.70E+3nMAssay Description:Ability to displace [3H]SCH-23,390 radioligand from bovine Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed