BDBM50115795 2,4-Bis-hydroxymethyl-8-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-8H-pyrido[2,3-d]pyrimidin-7-one::2,4-Bis-methoxymethyl-8-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-5,8-dihydro-6H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL307191

SMILES OCc1nc(CO)c2ccc(=O)n(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c2n1

InChI Key InChIKey=GCRKPEJIEZYAGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50115795   

TargetType-1 angiotensin II receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50115795(2,4-Bis-hydroxymethyl-8-[2'-(2H-tetrazol-5-yl)-bip...)
Affinity DataIC50: 44nMAssay Description:Compound was tested in vitro for inhibitory activity against human Angiotensin II receptor in cultured preadipocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50115795(2,4-Bis-hydroxymethyl-8-[2'-(2H-tetrazol-5-yl)-bip...)
Affinity DataIC50: 44nMAssay Description:Compound was tested for inhibition against Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed