BDBM50116292 3-(2',6'-Dimethoxy-biphenyl-4-yl)-2-[(1-phenyl-cyclopentanecarbonyl)-amino]-propionic acid::CHEMBL71577

SMILES COc1cccc(OC)c1-c1ccc(CC(NC(=O)C2(CCCC2)c2ccccc2)C(O)=O)cc1

InChI Key InChIKey=LPTLKRBMBJHFHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116292   

TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116292(3-(2',6'-Dimethoxy-biphenyl-4-yl)-2-[(1-phenyl-cyc...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of [125I]VCAM-Ig binding to human integrin alpha4-beta1 (VLA-4) of Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116292(3-(2',6'-Dimethoxy-biphenyl-4-yl)-2-[(1-phenyl-cyc...)
Affinity DataIC50: 110nMAssay Description:Inhibition of [125I]MAdCAM-Ig binding to human integrin alpha4-beta7 of RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed