BDBM50116358 CHEMBL3604359

SMILES CSC[C@@H]1CN(Cc2c[nH]c3c(O)ncnc23)C[C@H]1O

InChI Key InChIKey=DBPWKRQKYPFTJB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50116358   

TargetPurine nucleoside phosphorylase(Human)
Victoria University of Wellington

Curated by ChEMBL
LigandPNGBDBM50116358(CHEMBL3604359)
Affinity DataKi:  84nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Victoria University of Wellington

Curated by ChEMBL
LigandPNGBDBM50116358(CHEMBL3604359)
Affinity DataKi:  93nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Victoria University of Wellington

Curated by ChEMBL
LigandPNGBDBM50116358(CHEMBL3604359)
Affinity DataKi:  110nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Victoria University of Wellington

Curated by ChEMBL
LigandPNGBDBM50116358(CHEMBL3604359)
Affinity DataKi:  298nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed