BDBM50116838 CHEMBL3612922

SMILES Cc1cc(cnc1C(O)CN1CCN(C[C@H](O)c2ccc3C(=O)OCc3c2C)CC1)C#N

InChI Key InChIKey=XVHBSQZSXHVVKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116838   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116838(CHEMBL3612922)
Affinity DataIC50: 640nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116838(CHEMBL3612922)
Affinity DataIC50: 640nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed