BDBM50117182 2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL120995::Dinapsoline, (+/-)

SMILES Oc1ccc2C3CNCc4cccc(Cc2c1O)c34

InChI Key InChIKey=ZQTSNGJHMUKLOM-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50117182   

TargetD(2) dopamine receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50117182(Dinapsoline, (+/-) | CHEMBL120995 | 2,3,7,11b-Tetr...)
Affinity DataKi:  10.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117182(Dinapsoline, (+/-) | CHEMBL120995 | 2,3,7,11b-Tetr...)
Affinity DataIC50: 56nMAssay Description:In vitro inhibition of [125I]7-OH-PIPAT binding to Dopamine receptor D2 of rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117182(Dinapsoline, (+/-) | CHEMBL120995 | 2,3,7,11b-Tetr...)
Affinity DataKi:  56nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117182(Dinapsoline, (+/-) | CHEMBL120995 | 2,3,7,11b-Tetr...)
Affinity DataIC50: 67nMAssay Description:In vitro inhibition of [125I]SCH-23982 binding to Dopamine receptor D1 of rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117182(Dinapsoline, (+/-) | CHEMBL120995 | 2,3,7,11b-Tetr...)
Affinity DataKi:  67nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed