BDBM50117678 CHEMBL3613794

SMILES Oc1cc(F)ccc1CNc1ncccc1-c1ncccn1

InChI Key InChIKey=YTVDOVJPKJLMHL-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50117678   

TargetCaspase-6(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117678BDBM50117678(CHEMBL3613794)
Affinity DataKd:  270nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117678BDBM50117678(CHEMBL3613794)
Affinity DataIC50: 430nMAssay Description:Inhibition of Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) assessed as time-resolved luminescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117678BDBM50117678(CHEMBL3613794)
Affinity DataKd:  470nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCaspase-6(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117678BDBM50117678(CHEMBL3613794)
Affinity DataKd:  470nMAssay Description:Inhibition of Pro-caspase-6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed