BDBM50117933 (+)1-[4-(10-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone::CHEMBL340432

SMILES [O-][n+]1ccc(CC(=O)N2CCC(CC2)[C@H]2c3ncccc3CCc3cc(Cl)cc(Br)c23)cc1

InChI Key InChIKey=PPXJVZJWVHFFJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50117933   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117933((+)1-[4-(10-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50: 19nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed