BDBM50117974 CHEMBL3612833

SMILES O=C(NCCCN1CCC(Cc2ccccc2)CC1)c1ccc2ccccc2c1

InChI Key InChIKey=XFUBYPOXEIGKQC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50117974   

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50117974(CHEMBL3612833)
Affinity DataIC50: 100nMAssay Description:Inhibition of [3H]serotonin uptake at SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50117974(CHEMBL3612833)
Affinity DataIC50: 108nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction of serotonin reuptake using [3H]-SERT after 15 mins by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50117974(CHEMBL3612833)
Affinity DataIC50: 340nMAssay Description:Inhibition of [3H]norepinephrine uptake at NET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50117974(CHEMBL3612833)
Affinity DataIC50: 342nMAssay Description:Inhibition of human NET expressed in HEK293 cells assessed as reduction of serotonin reuptake using [3H]-NET after 15 mins by liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50117974(CHEMBL3612833)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at DAT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed