BDBM50118328 1-Benzo[b]thiophen-3-yl-3-[4-(1H-indol-4-yl)-piperazin-1-yl]-propan-1-ol;::CHEMBL133476

SMILES OC(CCN1CCN(CC1)c1cccc2[nH]ccc12)c1csc2ccccc12

InChI Key InChIKey=YGFDAPGDLKIWDD-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118328   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118328(1-Benzo[b]thiophen-3-yl-3-[4-(1H-indol-4-yl)-piper...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118328(1-Benzo[b]thiophen-3-yl-3-[4-(1H-indol-4-yl)-piper...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118328(1-Benzo[b]thiophen-3-yl-3-[4-(1H-indol-4-yl)-piper...)
Affinity DataIC50:  31.2nMAssay Description:Inhibition of (+)-8-OH-DPAT stimulated [35S]-GTP-gammaS, binding to 5-hydroxytryptamine 1A receptor in hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed