BDBM50118604 1-(benzo[b]thiophen-2-ylmethyl)-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperidine::1-Benzo[b]thiophen-2-ylmethyl-4-{2-[bis-(4-fluoro-phenyl)-methoxy]-ethyl}-piperidine::CHEMBL137020
SMILES Fc1ccc(cc1)C(OCCC1CCN(Cc2cc3ccccc3s2)CC1)c1ccc(F)cc1
InChI Key InChIKey=IBKOZXQELVZJBY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50118604
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Heights
Curated by ChEMBL
University Heights
Curated by ChEMBL
Affinity DataKi: 1.61nMAssay Description:Displacement of [125I]RTI55 from DAT in rat brain synaptosomesMore data for this Ligand-Target Pair
Affinity DataKi: 1.61nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 246nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]-RTI-55More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Heights
Curated by ChEMBL
University Heights
Curated by ChEMBL
Affinity DataKi: 246nMAssay Description:Displacement of [125I]RTI55 from SERT in rat brain synaptosomesMore data for this Ligand-Target Pair
Affinity DataIC50: 11.9nMAssay Description:Compound was tested for the inhibition of dopamine (DA) reuptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:Compound was tested for the inhibition of serotonin (5-HT) reuptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Compound was tested for the inhibition of norepinephrine (NE) reuptakeMore data for this Ligand-Target Pair