BDBM50118744 2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid::2-(carboxyformamido)-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylic acid::CHEMBL138806

SMILES OC(=O)C(=O)Nc1sc2COCCc2c1C(O)=O

InChI Key InChIKey=SNNOZMNTPOIDSI-UHFFFAOYSA-N

Data  12 KI

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50118744   

TargetReceptor-type tyrosine-protein phosphatase beta(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of PTPRBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Graduate University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  1.39E+4nMAssay Description:Binding affinity to PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Graduate University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  1.40E+4nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of PTPN2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Graduate University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  1.41E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase epsilon(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of PTPREMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  5.30E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  1.70E+5nMAssay Description:Inhibition of PTPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  1.70E+5nMpH: 5.5Assay Description:Inhibitory effect against human protein-tyrosine phosphatase alpha (PTPalpha), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  3.50E+5nMAssay Description:Inhibition of PTPN6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  3.60E+5nMAssay Description:Inhibition of PTPRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  3.60E+5nMpH: 5.5Assay Description:Inhibitory effect against protein-tyrosine phosphatase Lar, using p-nitrophenyl phosphate as substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed