BDBM50118745 5-(4-(benzyloxy)phenyl)-3-(carboxyformamido)thiophene-2-carboxylic acid::5-(4-Benzyloxy-phenyl)-3-(oxalyl-amino)-thiophene-2-carboxylic acid::CHEMBL343979

SMILES OC(=O)C(=O)Nc1cc(sc1C(O)=O)-c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=VQJPSLCBDAZVPK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118745   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118745(5-(4-(benzyloxy)phenyl)-3-(carboxyformamido)thioph...)
Affinity DataKi:  1.58E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118745(5-(4-(benzyloxy)phenyl)-3-(carboxyformamido)thioph...)
Affinity DataKi:  1.59E+4nMAssay Description:Binding affinity to PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118745(5-(4-(benzyloxy)phenyl)-3-(carboxyformamido)thioph...)
Affinity DataKi:  1.60E+4nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118745(5-(4-(benzyloxy)phenyl)-3-(carboxyformamido)thioph...)
Affinity DataKi:  6.50E+4nMpH: 5.5Assay Description:Inhibitory effect against human protein-tyrosine phosphatase alpha (PTPalpha), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed