BDBM50118749 2-(Oxalyl-amino)-thiophene-3-carboxylic acid::2-(carboxyformamido)thiophene-3-carboxylic acid::CHEMBL342612

SMILES OC(=O)C(=O)Nc1sccc1C(O)=O

InChI Key InChIKey=XIFSAFAFYIYHSU-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50118749   

TargetReceptor-type tyrosine-protein phosphatase beta(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of PTPRBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi:  6.00E+4nMAssay Description:Inhibition of PTPN6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi:  6.20E+4nMAssay Description:Inhibition of PTPN2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi:  1.07E+5nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi:  1.08E+5nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi:  1.08E+5nMAssay Description:Binding affinity to PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase epsilon(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi:  7.40E+5nMAssay Description:Inhibition of PTPREMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi:  1.70E+6nMAssay Description:Inhibition of PTPRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi:  1.70E+6nMpH: 5.5Assay Description:Inhibitory effect against human protein-tyrosine phosphatase alpha (PTPalpha), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi:  2.00E+6nMpH: 5.5Assay Description:Inhibitory effect against protein-tyrosine phosphatase Lar, using p-nitrophenyl phosphate as substrate at pH 5.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118749(2-(carboxyformamido)thiophene-3-carboxylic acid | ...)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of PTPRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed