BDBM50118914 CHEMBL343739::Phenyl-[(S)-2-(pyrrolidine-1-carbonyl)-pyrrolidin-1-yl]-methanone::Phenyl-[2-(pyrrolidine-1-carbonyl)-pyrrolidin-1-yl]-methanone

SMILES O=C([C@@H]1CCCN1C(=O)c1ccccc1)N1CCCC1

InChI Key InChIKey=HEWFDUPRLUFDCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50118914   

TargetProlyl endopeptidase(Pig)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50118914(Phenyl-[(S)-2-(pyrrolidine-1-carbonyl)-pyrrolidin-...)
Affinity DataIC50: 66nMAssay Description:In vitro inhibitory activity against prolyl oligopeptidase (POP) from pig brain; value ranges from (38-110)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50118914(Phenyl-[(S)-2-(pyrrolidine-1-carbonyl)-pyrrolidin-...)
Affinity DataIC50: 66nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed