BDBM50119226 2-[2-(2-Cyclopentyl-phenoxy)-acetylamino]-4-methyl-pentanoic acid (2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::CHEMBL321074

SMILES CC(C)C[C@H](NC(=O)COc1ccccc1C1CCCC1)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=ZUMYWWOOYMHLPE-JOHXPNBHSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119226   

TargetCaspase-6(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119226(2-[2-(2-Cyclopentyl-phenoxy)-acetylamino]-4-methyl...)
Affinity DataIC50:  3.37E+3nMAssay Description:Inhibitory concentration required against caspase-6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119226(2-[2-(2-Cyclopentyl-phenoxy)-acetylamino]-4-methyl...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibitory concentration against caspase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119226(2-[2-(2-Cyclopentyl-phenoxy)-acetylamino]-4-methyl...)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibitory concentration against caspase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119226(2-[2-(2-Cyclopentyl-phenoxy)-acetylamino]-4-methyl...)
Affinity DataIC50:  538nMAssay Description:Inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119226(2-[2-(2-Cyclopentyl-phenoxy)-acetylamino]-4-methyl...)
Affinity DataIC50:  197nMAssay Description:Inhibitory concentration against caspase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed