BDBM50119696 1-{4-[3-((S)-3-Amino-pyrrolidin-1-yl)-propoxy]-phenyl}-ethanone::CHEMBL319231

SMILES CC(=O)c1ccc(OCCCN2CC[C@H](N)C2)cc1

InChI Key InChIKey=PHNZBVSSQHIXIP-AWEZNQCLSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50119696   

TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119696(1-{4-[3-((S)-3-Amino-pyrrolidin-1-yl)-propoxy]-phe...)
Affinity DataKi:  676nMAssay Description:Binding affinity of the compound towards rat Histamine H3 receptor (For compound 11)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119696(1-{4-[3-((S)-3-Amino-pyrrolidin-1-yl)-propoxy]-phe...)
Affinity DataKi:  1.72E+3nMAssay Description:Binding affinity against rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119696(1-{4-[3-((S)-3-Amino-pyrrolidin-1-yl)-propoxy]-phe...)
Affinity DataKi:  3.10E+4nMAssay Description:Binding affinity of the compound towards human Histamine H2 receptor (For compound 11)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119696(1-{4-[3-((S)-3-Amino-pyrrolidin-1-yl)-propoxy]-phe...)
Affinity DataKi:  5.00E+4nMAssay Description:Binding affinity to the human Histamine H2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119696(1-{4-[3-((S)-3-Amino-pyrrolidin-1-yl)-propoxy]-phe...)
Affinity DataKi:  9.00E+4nMAssay Description:Binding affinity to the human Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119696(1-{4-[3-((S)-3-Amino-pyrrolidin-1-yl)-propoxy]-phe...)
Affinity DataKi:  1.00E+5nMAssay Description:Binding affinity of the compound towards human Histamine H1 receptor (For compound 11)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed