BDBM50120115 CHEMBL321862::N*4*-(2-Chloro-6-fluoro-phenyl)-N*7*-(2-dimethylamino-ethyl)-8-methoxy-imidazo[1,5-a]quinoxaline-4,7-diamine::N4-(2-chloro-6-fluorophenyl)-N7-(2-(dimethylamino)ethyl)-8-methoxyimidazo[1,5-a]quinoxaline-4,7-diamine

SMILES COc1cc2c(cc1NCCN(C)C)nc(Nc1c(F)cccc1Cl)c1cncn21

InChI Key InChIKey=OWCYOUGDIGYRQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120115   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120115(N4-(2-chloro-6-fluorophenyl)-N7-(2-(dimethylamino)...)
Affinity DataIC50: 5nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120115(N4-(2-chloro-6-fluorophenyl)-N7-(2-(dimethylamino)...)
Affinity DataIC50: 5nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed