BDBM50120135 4-(2-Chloro-6-methyl-phenylamino)-imidazo[1,5-a]quinoxaline-7-carboxylic acid amide::4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]quinoxaline-7-carboxamide::CHEMBL85979

SMILES Cc1cccc(Cl)c1Nc1nc2cc(ccc2n2cncc12)C(N)=O

InChI Key InChIKey=GXAFJIDQFLYLDD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50120135   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120135(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]quin...)
Affinity DataIC50: 30nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120135(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]quin...)
Affinity DataIC50: 30nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120135(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]quin...)
Affinity DataIC50: 30nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed