BDBM50120695 2-{3-[4-(3,5-Dimethoxy-benzyloxy)-phenyl]-3-methyl-2-oxo-pyrrolidin-1-yl}-N-hydroxy-propionamide::CHEMBL143451

SMILES COc1cc(COc2ccc(cc2)[C@]2(C)CCN([C@H](C)C(=O)NO)C2=O)cc(OC)c1

InChI Key InChIKey=FLJLPPYUZKFFLM-CMJOXMDJSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120695   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120695(2-{3-[4-(3,5-Dimethoxy-benzyloxy)-phenyl]-3-methyl...)
Affinity DataKi: >2.00E+3nMAssay Description:Affinity towards Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120695(2-{3-[4-(3,5-Dimethoxy-benzyloxy)-phenyl]-3-methyl...)
Affinity DataKi: >3.00E+3nMAssay Description:Affinity for Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120695(2-{3-[4-(3,5-Dimethoxy-benzyloxy)-phenyl]-3-methyl...)
Affinity DataKi: >5.00E+3nMAssay Description:Affinity towards Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120695(2-{3-[4-(3,5-Dimethoxy-benzyloxy)-phenyl]-3-methyl...)
Affinity DataIC50:  7nMAssay Description:Affinity for Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed