BDBM50120980 CHEMBL148542::N-(3-Phenoxy-pyridin-4-yl)-methanesulfonamide::N-(3-phenoxy-4-pyridinyl)methanesulfonamide::N-(3-phenoxypyridin-4-yl)methanesulfonamide

SMILES CS(=O)(=O)Nc1ccncc1Oc1ccccc1

InChI Key InChIKey=CQEDUEBRINEBGP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50120980   

TargetProstaglandin G/H synthase 1(Human)
University of Liege

Curated by ChEMBL
LigandPNGBDBM50120980(N-(3-phenoxypyridin-4-yl)methanesulfonamide | N-(3...)
Affinity DataIC50: 410nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Liege

Curated by ChEMBL
LigandPNGBDBM50120980(N-(3-phenoxypyridin-4-yl)methanesulfonamide | N-(3...)
Affinity DataIC50: 410nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Liege

Curated by ChEMBL
LigandPNGBDBM50120980(N-(3-phenoxypyridin-4-yl)methanesulfonamide | N-(3...)
Affinity DataIC50: 4.90E+3nMAssay Description:The inhibitory activity against Prostaglandin G/H synthase 1 measured as TXB2 production after blood coagulation using human Whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50120980(N-(3-phenoxypyridin-4-yl)methanesulfonamide | N-(3...)
Affinity DataIC50: 3.75E+4nMAssay Description:The inhibitory activity against cyclooxygenase Prostaglandin G/H synthase 2 (COX-2) measured as PGE-2 production after blood coagulation using human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50120980(N-(3-phenoxypyridin-4-yl)methanesulfonamide | N-(3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50120980(N-(3-phenoxypyridin-4-yl)methanesulfonamide | N-(3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed