BDBM50121212 CHEMBL3622372
SMILES C[C@@H]1COCCN1c1cc(=O)n2CC[C@H](N(Cc3cncc(Cl)c3)c2n1)C(F)(F)F
InChI Key InChIKey=SPDQRCUBFSRAFI-UHFFFAOYSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 25 hits for monomerid = 50121212
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Jiliang University
Curated by ChEMBL
China Jiliang University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human PIK3C3 using PI as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Jiliang University
Curated by ChEMBL
China Jiliang University
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P ELIS...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Jiliang University
Curated by ChEMBL
China Jiliang University
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Jiliang University
Curated by ChEMBL
China Jiliang University
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Jiliang University
Curated by ChEMBL
China Jiliang University
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human Vps34 by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Jiliang University
Curated by ChEMBL
China Jiliang University
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Competitive inhibition of recombinant human VPS34 in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Jiliang University
Curated by ChEMBL
China Jiliang University
Curated by ChEMBL
Affinity DataEC50: 1.20nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formationMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Georgetown University
Curated by ChEMBL
Georgetown University
Curated by ChEMBL
Affinity DataEC50: >10nMAssay Description:Inhibition of human PI3Kbeta assessed as reduction in PIP3 product complex formationMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Georgetown University
Curated by ChEMBL
Georgetown University
Curated by ChEMBL
Affinity DataEC50: >10nMAssay Description:Inhibition of human PI3Kbeta assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P E...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Jiliang University
Curated by ChEMBL
China Jiliang University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of Vps34 in human HeLa cells expressing GFP-FYVEMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Jiliang University
Curated by ChEMBL
China Jiliang University
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Competitive inhibition of VPS34 (unknown origin) incubated for 15 mins in presence of ATP by ELISAMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Georgetown University
Curated by ChEMBL
Georgetown University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of PI3K beta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of PI3K alpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Georgetown University
Curated by ChEMBL
Georgetown University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of PI3K gamma (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human mTOR by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Georgetown University
Curated by ChEMBL
Georgetown University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PI3Kgamma by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PI3Kdelta by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PI3Kalpha by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Georgetown University
Curated by ChEMBL
Georgetown University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PI3Kbeta by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Curtin University
Curated by ChEMBL
Curtin University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2alpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
Georgetown University
Curated by ChEMBL
Georgetown University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of PIK3C2B (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Curtin University
Curated by ChEMBL
Curtin University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of PIK3C2A (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
Georgetown University
Curated by ChEMBL
Georgetown University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2beta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase C2 domain-containing subunit gamma(Human)
Curtin University
Curated by ChEMBL
Curtin University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2gamma (unknown origin)More data for this Ligand-Target Pair