BDBM50121413 CHEMBL118852::Lithium; 4-(2,4-dichloro-benzoylamino)-3'-ethoxy-biphenyl-3-carboxylate

SMILES CCOc1cccc(c1)-c1ccc(NC(=O)c2ccc(Cl)cc2Cl)c(c1)C([O-])=O

InChI Key InChIKey=LGBAGNSJMLBFGM-UHFFFAOYSA-M

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121413   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121413(CHEMBL118852 | Lithium; 4-(2,4-dichloro-benzoylami...)
Affinity DataKi:  1.20E+3nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121413(CHEMBL118852 | Lithium; 4-(2,4-dichloro-benzoylami...)
Affinity DataKi: >1.00E+5nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121413(CHEMBL118852 | Lithium; 4-(2,4-dichloro-benzoylami...)
Affinity DataEC50:  300nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121413(CHEMBL118852 | Lithium; 4-(2,4-dichloro-benzoylami...)
Affinity DataEC50: >1.00E+5nMAssay Description:Transactivation potency was measured by luciferase activity in Caco- 2/TC7 cells transiently co-transfected for the fusion-protein Gal4-PPAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed