BDBM50121639 1-[3-(Adamantan-1-ylamino)-3,4-dihydro-1H-isoquinolin-2-yl]-2-dimethylamino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propan-1-one::CHEMBL356451

SMILES CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1NC12CC3CC(CC(C3)C1)C2

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121639   

TargetDelta-type opioid receptor(Rat)
National Institute of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50121639(1-[3-(Adamantan-1-ylamino)-3,4-dihydro-1H-isoquino...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity of compound towards the Opioid receptor delta 1 in rat synaptosomal membrane was determined using [3H]DPDPE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50121639(1-[3-(Adamantan-1-ylamino)-3,4-dihydro-1H-isoquino...)
Affinity DataKi:  1.12nMAssay Description:Binding affinity of compound towards the Opioid receptor mu 1 in rat synaptosomal membrane was determined using [3H]DAGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed