BDBM50121888 5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid ((S)-1-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide::CHEMBL29317

SMILES CCCCC(=O)NC1(C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC(N)=O)CCc2c(cccc2N(C)C)C1

InChI Key InChIKey=LSYZHBPXGYVTPN-UHFFFAOYSA-N

Data  4 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50121888   

TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121888BDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataEC50:  16nMAssay Description:Agonist activity against human melanocortin receptor hMC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121888BDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataEC50:  16nMAssay Description:Agonist activity against human melanocortin receptor hMC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121888BDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataIC50: 150nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121888BDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataIC50: 150nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121888BDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataEC50:  1.85E+3nMAssay Description:Agonist activity against human melanocortin receptor hMC1R at 50% maximum cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121888BDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataEC50:  1.85E+3nMAssay Description:Agonist activity against human melanocortin receptor hMC1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121888BDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataEC50:  1.85E+3nMAssay Description:Binding affinity towards human melanocortin receptor hMC1R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121888BDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataEC50:  1.85E+3nMAssay Description:Agonist activity against human melanocortin receptor hMC1R at 50% maximum cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121888BDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataIC50: 2.17E+4nMAssay Description:Binding affinity towards human melanocortin receptor hMC1R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121888BDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataIC50: 2.17E+4nMAssay Description:Binding affinity towards human melanocortin receptor hMC1R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed