BDBM50122205 (R)-4-{4-[3-(1H-Benzoimidazol-2-ylamino)-propylamino]-5-methyl-2-oxo-2H-pyrimidin-1-yl}-3-benzyloxycarbonylamino-butyric acid::CHEMBL294953

SMILES Cc1cn(C[C@@H](CC(O)=O)NC(=O)OCc2ccccc2)c(=O)nc1NCCCNc1nc2ccccc2[nH]1

InChI Key InChIKey=WBNIBVOJNZUYKZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50122205   

TargetIntegrin alpha-V/beta-3(Human)
Basf

Curated by ChEMBL
LigandPNGBDBM50122205((R)-4-{4-[3-(1H-Benzoimidazol-2-ylamino)-propylami...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory concentration against alphaV-beta3 integrin using vitronectin ELISA assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Basf

Curated by ChEMBL
LigandPNGBDBM50122205((R)-4-{4-[3-(1H-Benzoimidazol-2-ylamino)-propylami...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory concentration against alphaV-beta3 integrin using vitronectin ELISA assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Basf

Curated by ChEMBL
LigandPNGBDBM50122205((R)-4-{4-[3-(1H-Benzoimidazol-2-ylamino)-propylami...)
Affinity DataIC50: 300nMAssay Description:Inhibition of alphaV-beta5 integrin binding to vitronectin in adhesion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Basf

Curated by ChEMBL
LigandPNGBDBM50122205((R)-4-{4-[3-(1H-Benzoimidazol-2-ylamino)-propylami...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of alphaIIb-beta3 integrin binding to fibrinogen in ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed