BDBM50122345 (S)-3-[4-((Z)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-phenyl]-2-ethoxy-propionic acid::CHEMBL421729

SMILES CCO[C@@H](Cc1ccc(OC\C=C(\c2ccccc2)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O

InChI Key InChIKey=IILKLIPGEXMTPN-WFRJPOHTSA-N

Data  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50122345   

LigandPNGBDBM50122345((S)-3-[4-((Z)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...)
Affinity DataEC50:  1.70E+3nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122345((S)-3-[4-((Z)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...)
Affinity DataEC50:  700nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122345((S)-3-[4-((Z)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...)
Affinity DataEC50:  700nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122345((S)-3-[4-((Z)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...)
Affinity DataEC50:  1.70E+3nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122345((S)-3-[4-((Z)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...)
Affinity DataEC50:  891nMAssay Description:Transactivation of Homo sapiens (human) PPARalpha assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122345((S)-3-[4-((Z)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...)
Affinity DataEC50:  700nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50122345((S)-3-[4-((Z)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...)
Affinity DataEC50:  2.20E+3nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor delta (PPAR delta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50122345((S)-3-[4-((Z)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...)
Affinity DataEC50:  1.70E+3nMAssay Description:Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122345((S)-3-[4-((Z)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...)
Affinity DataEC50:  1.70E+3nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor gamma (PPAR gamma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed