BDBM50122677 4'-Oxazol-2-yl-2'-[(2,2,2-trifluoro-ethylamino)-methyl]-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL29420

SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CNCC(F)(F)F)-c2ncco2)c1C

InChI Key InChIKey=ZHRNJYRTUCXIIO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122677   

TargetEndothelin-1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122677(4'-Oxazol-2-yl-2'-[(2,2,2-trifluoro-ethylamino)-me...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122677(4'-Oxazol-2-yl-2'-[(2,2,2-trifluoro-ethylamino)-me...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibitory activity against human endothelin B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed