BDBM50123028 CHEMBL3623220

SMILES [H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])c3cc(NC(=O)c4ccncc4)c(O)cc3CC[C@@]21[H]

InChI Key InChIKey=TXRBRWIJCHJAHH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123028   

TargetAromatase(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50123028(CHEMBL3623220)
Affinity DataKi:  2.10E+3nMAssay Description:Competitive inhibition of human aromatase extracted from placental microsomes after 5 mins by Dixon plot analysis in presence of [1beta-3H]ADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2017
Entry Details Article
PubMed
TargetAromatase(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50123028(CHEMBL3623220)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human placental aromatase assessed as conversion of 3H2O from [1beta-3H]AD after 20 mins by Siiteri and Thompson methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed