BDBM50123131 CHEMBL137419::{(3S,4S)-3-[4-(Allyl-pyridin-2-yl-amino)-piperidin-1-ylmethyl]-4-phenyl-pyrrolidin-1-yl}-cyclohexyl-methanone

SMILES C=CCN(C1CCN(C[C@H]2CN(C[C@@H]2c2ccccc2)C(=O)C2CCCCC2)CC1)c1ccccn1

InChI Key InChIKey=RHFUWIXPHXRNRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123131   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123131({(3S,4S)-3-[4-(Allyl-pyridin-2-yl-amino)-piperidin...)
Affinity DataIC50: 6nMAssay Description:Displacement inhibition of 125-I labeled MIP-alpha from CCR5 receptor expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123131({(3S,4S)-3-[4-(Allyl-pyridin-2-yl-amino)-piperidin...)
Affinity DataIC50: 11nMAssay Description:Inhibition over 48 hr of BAL strain HIV infrction of HeLa Magi cells expressing CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed