BDBM50123132 (R)-3-Cyclobutyl-2-[(3S,4S)-3-[4-(cyclopropylmethyl-pyrimidin-2-yl-amino)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-propionic acid::CHEMBL137327

SMILES OC(=O)[C@@H](CC1CCC1)N1C[C@H](CN2CCC(CC2)N(CC2CC2)c2ncccn2)[C@H](C1)c1cccc(F)c1

InChI Key InChIKey=IJCIMXNTVMTNCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123132   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123132((R)-3-Cyclobutyl-2-[(3S,4S)-3-[4-(cyclopropylmethy...)
Affinity DataIC50: 1.10nMAssay Description:Displacement inhibition of 125-I labeled MIP-alpha from CCR5 receptor expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123132((R)-3-Cyclobutyl-2-[(3S,4S)-3-[4-(cyclopropylmethy...)
Affinity DataIC50: 11nMAssay Description:Inhibition over 48 hr of BAL strain HIV infrction of HeLa Magi cells expressing CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed