BDBM50123146 ((3S,4S)-3-phenyl-4-((4-(propyl(pyridin-2-yl)amino)piperidin-1-yl)methyl)pyrrolidin-1-yl)(pyrrolidin-1-yl)methanone::CHEMBL137524::{(3S,4S)-3-Phenyl-4-[4-(propyl-pyridin-2-yl-amino)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-pyrrolidin-1-yl-methanone

SMILES CCCN(C1CCN(C[C@H]2CN(C[C@@H]2c2ccccc2)C(=O)N2CCCC2)CC1)c1ccccn1

InChI Key InChIKey=VFWZVVDVMDAVKC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123146   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123146({(3S,4S)-3-Phenyl-4-[4-(propyl-pyridin-2-yl-amino)...)
Affinity DataIC50: 9nMAssay Description:Displacement inhibition of 125-I labeled MIP-alpha from CCR5 receptor expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123146({(3S,4S)-3-Phenyl-4-[4-(propyl-pyridin-2-yl-amino)...)
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]MIP1alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123146({(3S,4S)-3-Phenyl-4-[4-(propyl-pyridin-2-yl-amino)...)
Affinity DataIC50: 300nMAssay Description:Inhibition over 48 hr of BAL strain HIV infrction of HeLa Magi cells expressing CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed