BDBM50123310 1,3-Diethyl-5-(1-methyl-1H-indol-3-ylmethylene)-2-thioxo-dihydro-pyrimidine-4,6-dione::CHEMBL359346

SMILES CCN1C(=O)C(=Cc2cn(C)c3ccccc23)C(=O)N(CC)C1=S

InChI Key InChIKey=MBDMELPJKDBUGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123310   

TargetTumor necrosis factor receptor superfamily member 1A(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123310BDBM50123310(1,3-Diethyl-5-(1-methyl-1H-indol-3-ylmethylene)-2-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed