BDBM50123372 CHEMBL3623251

SMILES O=c1[nH]c2ccc(cc2c(=O)[nH]1)S(=O)(=O)Nc1ccccc1-c1ccccc1

InChI Key InChIKey=PNCTYSQEQDDRNS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123372   

TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50123372(CHEMBL3623251)
Affinity DataIC50:  1.37E+5nMAssay Description:Inhibition of human recombinant SIRT6 deacetylase activity using Arg-His-Lys-Lys(AC)-AMC as a substrate by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50123372(CHEMBL3623251)
Affinity DataIC50:  1.37E+5nMAssay Description:Inhibition of human SIRT6 deacetylase activity using Arg-His-Lys-Lys(AC)-AMC as a substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed