BDBM50123724 2,3-Dihydro-1H-cyclopenta[a]naphthalene-2-carboxylic acid [5-(2-ethyl-pyridin-4-yl)-1H-pyrazol-3-yl]-amide::CHEMBL422012

SMILES CCc1cc(ccn1)-c1cc(NC(=O)C2Cc3ccc4ccccc4c3C2)[nH]n1

InChI Key InChIKey=MYKLSWAEPUDUOD-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50123724   

TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50123724(2,3-Dihydro-1H-cyclopenta[a]naphthalene-2-carboxyl...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of [125I]-PYY binding to human recombinant Neuropeptide Y receptor type 5 in LMtk-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50123724(2,3-Dihydro-1H-cyclopenta[a]naphthalene-2-carboxyl...)
Affinity DataKi:  7.30nMAssay Description:Inhibition of [125I]-PYY binding to human recombinant Neuropeptide Y receptor type 5 in LMtk-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50123724(2,3-Dihydro-1H-cyclopenta[a]naphthalene-2-carboxyl...)
Affinity DataKi:  7.30nMAssay Description:Inhibition of [125I]-PYY binding to human recombinant Neuropeptide Y receptor type 5 in LMtk-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50123724(2,3-Dihydro-1H-cyclopenta[a]naphthalene-2-carboxyl...)
Affinity DataIC50:  14nMAssay Description:Antagonistic activity of compound was determined by its ability to inhibit NPY induced [Ca2+]i increases in CHO cells which expressed the recombinant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50123724(2,3-Dihydro-1H-cyclopenta[a]naphthalene-2-carboxyl...)
Affinity DataIC50:  14nMAssay Description:Antagonistic activity of compound was determined by its ability to inhibit NPY induced [Ca2+]i increases in CHO cells which expressed the recombinant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed