BDBM50123871 (4-Chloro-phenyl)-(furan-2-carbonyl)-thiocarbamic acid O-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl] ester::CHEMBL355113::O-2-(1,3-dioxoisoindolin-2-yl)ethyl 4-chlorophenyl(furan-2-carbonyl)carbamothioate

SMILES Clc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1ccco1

InChI Key InChIKey=PNQFAKVOOYJITA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123871   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123871((4-Chloro-phenyl)-(furan-2-carbonyl)-thiocarbamic ...)
Affinity DataIC50:  2.30E+3nMAssay Description:Activity of selected HIV-1 N-acylthiocarbamates in enzyme assay against Virion-Associated reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123871((4-Chloro-phenyl)-(furan-2-carbonyl)-thiocarbamic ...)
Affinity DataEC50:  7nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed