BDBM50124193 (S)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine::CHEMBL169459

SMILES C([C@@H]1CCNC(=N1)c1ccccc1)N1CCN(CC1)c1ccccc1

InChI Key InChIKey=BJWYIHWMKMZYRS-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50124193   

TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124193((S)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4...)
Affinity DataKi:  310nMAssay Description:Effective concentration for [3H]thymidine uptake in growing CHO cells stably expressing the dopamine D4.2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124193((S)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4...)
Affinity DataKi:  1.30E+4nMAssay Description:In vitro ability to displace [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124193((S)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4...)
Affinity DataKi:  2.90E+4nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D2 long in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124193((S)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4...)
Affinity DataKi:  3.00E+4nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D2 short in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124193((S)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4...)
Affinity DataKi:  3.90E+4nMAssay Description:In vitro Binding affinity towards dopamine D1 receptor using bovine striatal membrane preparations and antagonist [3H]-SCH- 23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed