BDBM50124198 (R)-2-Phenyl-5-(4-phenyl-piperazin-1-yl)-4,5,6,7-tetrahydro-1H-[1,3]diazepine::CHEMBL354748

SMILES C1CN(CCN1[C@H]1CCNC(=NC1)c1ccccc1)c1ccccc1

InChI Key InChIKey=JCXPHDPIKCCHEL-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50124198   

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124198((R)-2-Phenyl-5-(4-phenyl-piperazin-1-yl)-4,5,6,7-t...)
Affinity DataKi:  3.30E+3nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D3 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124198((R)-2-Phenyl-5-(4-phenyl-piperazin-1-yl)-4,5,6,7-t...)
Affinity DataKi:  4.40E+3nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D4 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124198((R)-2-Phenyl-5-(4-phenyl-piperazin-1-yl)-4,5,6,7-t...)
Affinity DataKi:  1.40E+4nMAssay Description:In vitro binding affinity to displace [3H]-spiperone from the cloned human dopamine receptor D2 short in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124198((R)-2-Phenyl-5-(4-phenyl-piperazin-1-yl)-4,5,6,7-t...)
Affinity DataKi:  1.90E+4nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D2 long in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124198((R)-2-Phenyl-5-(4-phenyl-piperazin-1-yl)-4,5,6,7-t...)
Affinity DataKi:  2.30E+4nMAssay Description:In vitro Binding affinity towards dopamine D1 receptor using bovine striatal membrane preparations and antagonist [3H]-SCH- 23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed