BDBM50124274 3-(2'-Methoxy-biphenyl-4-yl)-2-{[1-((S)-toluene-2-sulfonyl)-cyclohexanecarbonyl]-amino}-propionic acid::CHEMBL354798

SMILES COc1ccccc1-c1ccc(C[C@H](NC(=O)C2(CCCCC2)S(=O)(=O)c2ccccc2C)C(O)=O)cc1

InChI Key InChIKey=SAYYIMRPRXVLIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124274   

TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124274(3-(2'-Methoxy-biphenyl-4-yl)-2-{[1-((S)-toluene-2-...)
Affinity DataIC50: 2.70nMAssay Description:Binding affinity towards VLA-4 (alpha4 beta-1) receptor in human Jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124274(3-(2'-Methoxy-biphenyl-4-yl)-2-{[1-((S)-toluene-2-...)
Affinity DataIC50: 149nMAssay Description:Inhibition of [125I]-VCAM-Ig binding to human integrin alpha4-beta7 receptor in RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed