BDBM50124395 4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-benzoic acid::CHEMBL367002

SMILES CCCc1c(OCCCCOc2ccc(cc2)C(O)=O)ccc2c(noc12)-c1ccccc1

InChI Key InChIKey=VFUIUWFGLWYTFT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124395   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124395BDBM50124395(4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-...)
Affinity DataKi:  920nMAssay Description:In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124395BDBM50124395(4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-...)
Affinity DataKi: >5.30E+3nMAssay Description:Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124395BDBM50124395(4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-...)
Affinity DataKi: >1.40E+4nMAssay Description:In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed