BDBM50124682 2-Cyclohexylmethyl-4-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2H-pyridazin-3-one::CHEMBL158148

SMILES CS(=O)(=O)c1ccc(cc1)-c1cnn(CC2CCCCC2)c(=O)c1-c1ccc(F)cc1

InChI Key InChIKey=VSFNTSQLLVIKMG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124682   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50124682(2-Cyclohexylmethyl-4-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity against sensitive U-937 microsomal prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50124682(2-Cyclohexylmethyl-4-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 stably transfected in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50124682(2-Cyclohexylmethyl-4-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50:  410nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 stably transfected in Human whole blood (HWB) cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed