BDBM50125136 2-[2,3']Bipyridinyl-6'-yl-1-(2,3-dihydro-benzofuran-5-yl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL163905

SMILES C1Cc2cc(ccc2O1)C1N(CCc2c1[nH]c1ccccc21)c1ccc(cn1)-c1ccccn1

InChI Key InChIKey=WBTKLEFBLWJDCP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125136   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125136(2-[2,3']Bipyridinyl-6'-yl-1-(2,3-dihydro-benzofura...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125136(2-[2,3']Bipyridinyl-6'-yl-1-(2,3-dihydro-benzofura...)
Affinity DataKi:  4nMAssay Description:Binding affinity to PDE5 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125136(2-[2,3']Bipyridinyl-6'-yl-1-(2,3-dihydro-benzofura...)
Affinity DataKi:  4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125136(2-[2,3']Bipyridinyl-6'-yl-1-(2,3-dihydro-benzofura...)
Affinity DataKi:  4nMAssay Description:Inhibition of human corpus cavernosum PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed