BDBM50125177 CHEMBL162768::N-[5-Fluoro-2-((7bS,11aR)-4-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butyryl)-phenyl]-acetamide

SMILES CC(=O)Nc1cc(F)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13

InChI Key InChIKey=FHQYCPGXTQGPMU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125177   

Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125177(N-[5-Fluoro-2-((7bS,11aR)-4-6,7,8,9,11,11a-hexahyd...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]DOI as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125177(N-[5-Fluoro-2-((7bS,11aR)-4-6,7,8,9,11,11a-hexahyd...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards DA D2 receptor using [3H]N-methyl-spiperone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125177(N-[5-Fluoro-2-((7bS,11aR)-4-6,7,8,9,11,11a-hexahyd...)
Affinity DataKi:  222nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2C receptor using [125I]DOI as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed