BDBM50125239 3-(3-Amino-4-chloro-phenyl)-5-pyrazol-1-ylmethyl-4,5-dihydro-isoxazole-5-carboxylic acid [5-(2-sulfamoyl-phenyl)-pyridin-2-yl]-amide::CHEMBL267387

SMILES Nc1cc(ccc1Cl)C1=NOC(Cn2cccn2)(C1)C(=O)Nc1ccc(cn1)-c1ccccc1S(N)(=O)=O

InChI Key InChIKey=SAZSSIWQOHGUHM-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50125239   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125239(3-(3-Amino-4-chloro-phenyl)-5-pyrazol-1-ylmethyl-4...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity against factor Xa using human purified enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125239(3-(3-Amino-4-chloro-phenyl)-5-pyrazol-1-ylmethyl-4...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against factor Xa using human purified enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125239(3-(3-Amino-4-chloro-phenyl)-5-pyrazol-1-ylmethyl-4...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibitory activity against Rabbit factor Xa was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125239(3-(3-Amino-4-chloro-phenyl)-5-pyrazol-1-ylmethyl-4...)
Affinity DataKi: >1.60E+3nMAssay Description:Inhibitory activity against trypsin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125239(3-(3-Amino-4-chloro-phenyl)-5-pyrazol-1-ylmethyl-4...)
Affinity DataKi: >1.60E+3nMAssay Description:Inhibitory activity against trypsin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125239(3-(3-Amino-4-chloro-phenyl)-5-pyrazol-1-ylmethyl-4...)
Affinity DataKi: >2.10E+4nMAssay Description:Inhibitory activity against thrombin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125239(3-(3-Amino-4-chloro-phenyl)-5-pyrazol-1-ylmethyl-4...)
Affinity DataKi: >2.10E+4nMAssay Description:Inhibitory activity against thrombin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed