BDBM50125242 3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamino-methyl)-4,5-dihydro-isoxazole-5-carboxylic acid [5-(2-sulfamoyl-phenyl)-pyridin-2-yl]-amide::CHEMBL7626

SMILES CS(=O)(=O)NCC1(CC(=NO1)c1ccc(Cl)c(N)c1)C(=O)Nc1ccc(cn1)-c1ccccc1S(N)(=O)=O

InChI Key InChIKey=ZVDBIMWPWVSMPA-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50125242   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory activity against factor Xa using human purified enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi:  1.90nMAssay Description:Inhibitory activity against factor Xa using human purified enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi:  2.30nMAssay Description:Inhibitory activity against Rabbit factor Xa was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi:  240nMAssay Description:Inhibitory activity against Rabbit factor Xa was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi:  800nMAssay Description:Inhibitory activity against thrombin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibitory activity against thrombin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi: >4.20E+3nMAssay Description:Inhibitory activity against trypsin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi: >8.00E+3nMAssay Description:Inhibitory activity against trypsin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi: >8.00E+3nMAssay Description:Inhibitory activity against trypsin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi: >2.10E+4nMAssay Description:Inhibitory activity against thrombin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed