BDBM50125521 CHEMBL16804::Propyl-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester

SMILES CCCNC(=O)O[C@H]1CC[C@](CNC(=O)c2ccccc2OC)(CC1)c1ccccc1

InChI Key InChIKey=IYMWLYWBYFPVAA-IHRKKFBRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125521   

TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125521(CHEMBL16804 | Propyl-carbamic acid 4-[(2-methoxy-b...)
Affinity DataIC50:  5nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125521(CHEMBL16804 | Propyl-carbamic acid 4-[(2-methoxy-b...)
Affinity DataIC50:  50nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125521(CHEMBL16804 | Propyl-carbamic acid 4-[(2-methoxy-b...)
Affinity DataIC50:  273nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed