BDBM50126322 4-Cyano-5-naphthalen-1-yl-3,6-dihydro-2H-pyridine-1-carboxylic acid (3-bromo-4-cyano-benzyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amide::CHEMBL29503

SMILES Cn1cncc1CN(Cc1ccc(C#N)c(Br)c1)C(=O)N1CCC(C#N)=C(C1)c1cccc2ccccc12

InChI Key InChIKey=XCKIUXVZLPDAPE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126322   

LigandPNGBDBM50126322(4-Cyano-5-naphthalen-1-yl-3,6-dihydro-2H-pyridine-...)
Affinity DataEC50: >1nMAssay Description:Inhibition of Ras farnesylation in Human Ha-Ras oncogene-transformed BALB/c 3T3 cells (EJ3 cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126322(4-Cyano-5-naphthalen-1-yl-3,6-dihydro-2H-pyridine-...)
Affinity DataIC50: 3.10nMAssay Description:In vitro inhibition of farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126322(4-Cyano-5-naphthalen-1-yl-3,6-dihydro-2H-pyridine-...)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibition of geranylgeranyltransferase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed