BDBM50126618 4-(N-benzyl-4-methoxyphenylsulfonamido)-8-tert-butyl-N-hydroxyquinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-tert-butyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL34660

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2c(cccc12)C(C)(C)C)C(=O)NO

InChI Key InChIKey=NYEXRVCCRODWLT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50126618   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126618(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-ter...)
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against matrix metalloprotease 9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126618(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-ter...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against matrix metalloprotease 13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126618(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-ter...)
Affinity DataIC50: 401nMAssay Description:Inhibitory activity against TACE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50126618(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-ter...)
Affinity DataIC50: 3.09E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50126618(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-ter...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity against matrix metalloprotease 1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed